Abstract: Acute ocular hypertension is a leading cause of retinal damage, vision impairment and even blindness during the acute attack of glaucoma. The rapid elevation of IOP in a short period of time can induce retinal ganglion cell apoptosis and tissue damage in all retinal layers (retinal thinning, reduction of retinal cells, changes of blood perfusion) through the mechanism of ischemia reperfusion injury, and the visual function (visual acuity, visual field, electrophysiological examination ) will change as well. (Int Rev Ophthalmol, 2022, 46: 80-84)

Key words: glaucoma, acute ocular hypertension, retina